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Test ID: PAMY Amylase, Pancreatic, Serum

Reporting Name

Amylase, Pancreatic, S

Useful For

Aiding in the evaluation of acute pancreatitis


This test is not useful for diagnosing or characterizing pancreatic cancer or cysts.

Specimen Type


Advisory Information

For amylase pancreatic cyst or fluid testing, order AMLPC / Amylase, Pancreatic Cyst Fluid.

For amylase testing using other body fluid specimens (eg, peritoneal, pleural), order AMBF / Amylase, Body Fluid.

Specimen Required

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot 1 mL of serum into plastic vial. Send refrigerated.

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 30 days
  Frozen  30 days
  Ambient  7 days

Reference Values

0-<24 months: 0-20 U/L

2-<18 years: 9-35 U/L

≥18 years: 13-53 U/L

Day(s) and Time(s) Performed

Monday through Saturday; Continuously

Test Classification

This test has been cleared, approved or is exempt by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
PAMY Amylase, Pancreatic, S 1805-1


Result ID Test Result Name Result LOINC Value
PAMY Amylase, Pancreatic, S 1805-1

Clinical Information

Amylases degrade complex carbohydrates (starches) into simple sugars. Two isoenzymes, pancreatic and salivary, are found in serum. Serum pancreatic amylase should always be interpreted in a context of total amylase to determine the relative contribution of salivary and pancreatic isoenzymes.


Imaging tests have become the diagnostic tests of choice for diagnosing pancreatitis. Pancreatic isoamylase may be used as an adjunct to totally serum amylase, serum lipase, and imaging tests.


Increased concentrations of pancreatic amylase isoenzymes in a context of elevated total serum amylase may indicate pancreatitis.

Clinical Reference

Panteghini M: Laboratory evaluation of pancreatic diseases. Biochimica Clinica. 2010;34(1):19-25

Analytic Time

1 day (not reported on Sunday)

Method Name

Colorimetric Reaction


If not ordering electronically, complete, print, and send a Gastroenterology and Hepatology Client Test Request (T728) with the specimen.

Mayo Clinic Laboratories | Gastroenterology Catalog Additional Information: